Eclanamine

Eclanamine
Systematic (IUPAC) name
	N-(3,4-dichlorophenyl)-N-[(1R,2R)-2-(dimethylamino)cyclopentyl]propanamide
Identifiers
CAS Number	71027-14-0; 67450-45-7 (maleate)
ATC code	None
PubChem	CID: 130380
ChemSpider	115358
UNII	5Y67H9W4KQ
Chemical data
Formula	C16H22Cl2N2O
Molecular mass	329.26 g/mol
	SMILES Clc2ccc(N(C(=O)CC)[C@@H]1CCC[C@H]1N(C)C)cc2Cl ;
	InChI InChI=1S/C16H22Cl2N2O/c1-4-16(21)20(11-8-9-12(17)13(18)10-11)15-7-5-6-14(15)19(2)3/h8-10,14-15H,4-7H2,1-3H3/t14-,15-/m1/s1 ; Key:YCRFSKUCDBJWLX-HUUCEWRRSA-N ;

Eclanamine (U-48,753) is a drug which was patented as an antidepressant, but was never marketed.^[1] It acts by inhibiting the reuptake of serotonin and norepinephrine.^[2] Eclanamine was discovered by accident as a derivative of the κ-opioid receptor agonist U-50,488.^[2]

References