Eprobemide

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Eprobemide.svg
Systematic (IUPAC) name
4-Chloro-N-[3-(4-morpholinyl)propyl]benzamide
Clinical data
Trade names Befol (RU)
Legal status
  • ℞ (Prescription only)
Routes of
administration
Oral
Identifiers
CAS Number 87940-60-1
PubChem CID: 65659
ChemSpider 59094
ChEMBL CHEMBL2104298
Synonyms Befol
Chemical data
Formula C14H19ClN2O2
Molecular mass 282.77 g/mol
  • C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
  • InChI=1S/C14H19ClN2O2/c15-13-4-2-12(3-5-13)14(18)16-6-1-7-17-8-10-19-11-9-17/h2-5H,1,6-11H2,(H,16,18)
  • Key:YYFGRAGNYHYWEZ-UHFFFAOYSA-N

Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol).[1] It is a non-competitive reversible inhibitor of monoamine oxidase A[2][3] that exhibits selective action on serotonin deamination.[4] Eprobemide differs from moclobemide only in linker that connects morpholine fragment with chlorobenzamide—moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.[5]

References

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  4. Eprobemide, ChemIDplus
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