Fatty acid-binding protein
The fatty-acid-binding proteins (FABPs) are a family of transport proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids.[1][2] These proteins are thought to facilitate the transfer of fatty acids between extra- and intracellular membranes.[3] Some family members are also believed to transport lipophilic molecules from outer cell membrane to certain intracellular receptors such as PPAR.[4] Levels of fatty-acid-binding protein have been shown to decline with ageing in the mouse brain, possibly contributing to age-associated decline in synaptic activity.[5]
Family members
Members of this family include:
| Protein name | Gene | Tissue distribution | Comment |
|---|---|---|---|
| FABP 1 | FABP1 | liver | |
| FABP 2 | FABP2 | intestinal | |
| FABP 3 | FABP3 | muscle and heart | mammary-derived growth inhibitor |
| FABP 4 | FABP4 | adipocyte | |
| FABP 5 | FABP5 | epidermal | psoriasis-associated |
| FABP 6 | FABP6 | ileal | gastrotropin |
| FABP 7 | FABP7 | brain | |
| FABP 8 | PMP2 | peripheral nervous system | peripheral myelin protein 2 |
| FABP 9 | FABP9 | ||
| FABP 11 | fabp11 | restricted to fishes | |
| FABP 12 | FABP12 | presence shown in human retinoblastoma cell lines, rodent retina and testis.[6] | |
| FABP 5-like 1 | FABP5L1 | ||
| FABP 5-like 2 | FABP5L2 | ||
| FABP 5-like 3 | FABP5L3 | ||
| FABP 5-like 4 | FABP5L4 | ||
| FABP 5-like 5 | FABP5L5 | ||
| FABP 5-like 6 | FABP5L6 | ||
| FABP 5-like 7 | FABP5L7 |
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
External links
- Fatty Acid-Binding Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
<templatestyles src="Asbox/styles.css"></templatestyles>
 |
This protein-related article is a stub. You can help Wikipedia by expanding it. |
