Fetal scalp blood testing
Two constituents that are commonly tested by this method are pH and lactate, both being indicators of acid base homeostasis. A low pH and high level of lactate indicate that there is acidosis, which in turn is associated with hypoxia.
pH and lactate appear to have the same sensitivity in indicating hypoxia during labour. Analysis of pH requires a relatively large amount of blood (30-50 μl), and sampling failure rates of 11-20% have been reported. Analysis of lactate only requires 5 μl of blood.
|Normal||>7.25||< 4.2 mmol/l||< 38 mg/dL|
|Pre-acidemia||7.21-7.25||4.2-4.8 mmol/l||38-43 mg/dL|
|Acidemia||< 7.21||> 4.8 mmol/l||> 43 mg/dL|
- "Fetal scalp pH testing: MedlinePlus Medical Encyclopedia". Retrieved 2010-01-17.
- Wiberg-Itzel, E.; Lipponer, C.; Norman, M.; Herbst, A.; Prebensen, D.; Hansson, A.; Bryngelsson, A. -L.; Christoffersson, M.; Sennström, M.; Wennerholm, U. -B.; Nordström, L. (2008). "Determination of pH or lactate in fetal scalp blood in management of intrapartum fetal distress: Randomised controlled multicentre trial". BMJ. 336 (7656): 1284–1287. PMC . PMID 18503103. doi:10.1136/bmj.39553.406991.25.
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