Flavokavain B
From Infogalactic: the planetary knowledge core
| 200px | |
| Names | |
|---|---|
| IUPAC name
(E)-1-(2-Hydroxy-4,6-dimethoxy-phenyl)-3-phenyl-propenone
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| Other names
2'-hydroxy-4',6'-dimethoxychalcone
Flavokawain B |
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| Identifiers | |
1775-97-9  |
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| 2059845 | |
| Jmol 3D model | Interactive image |
| PubChem | 5356121 |
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| Properties | |
| C17H16O4 | |
| Molar mass | 284.31 g·mol−1 |
| Vapor pressure | {{{value}}} |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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 verify (what is  ?) |
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| Infobox references | |
Flavokavain B is a flavokavain found in the kava plant.[1] In 2010 a paper was published identifying it as a hepatotoxin.[2] Another paper published in 2013 suggests that Flavokavain B might be effective in killing bone cancer cells by pointing out evidence of apoptosis and cell cycle arrest by Flacokavain B treatment with less toxicity than the standard treatments.[3] Flavokavain B has been demonstrated to possess potent apoptotic abilities.[4]
See also
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Zhou P., Gross S., Liu J.-H., Yu B.-Y., Feng L.-L., Nolta J., Sharma V., Piwnica-Worms D., Qiu S.X 'Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways . FASEB Journal 2010 24:12 (4722-4732)
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
External links
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