Flutrimazole

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Flutrimazole
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Systematic (IUPAC) name
(RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 119006-77-8 YesY
ATC code D01AC16 (WHO) G01AF18
PubChem CID: 3401
ChemSpider 3284 YesY
UNII 776S0UP252 YesY
KEGG D07193 YesY
ChEBI CHEBI:82864 N
ChEMBL CHEMBL2107430
Chemical data
Formula C22H16F2N2
Molecular mass 346.373 g/mol
  • Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4
  • InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H YesY
  • Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Flutrimazole is a wide spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol-14-demethylase.

References

  • The Merck Index, 12th Edition. 4247


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