HEYL

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Hairy/enhancer-of-split related with YRPW motif-like protein is a protein that in humans is encoded by the HEYL gene.[1][2][3]

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.[3]

References

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Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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