Halcinonide

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Halcinonide
Halcinonide.png
Systematic (IUPAC) name
(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-6b-(chloroacetyl)-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-tetradecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
Clinical data
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a682272
Routes of
administration
Topical
Identifiers
CAS Number 3093-35-4 YesY
ATC code D07AD02 (WHO)
PubChem CID: = 443943 =
ChemSpider 391997 N
UNII SI86V6QNEG N
ChEMBL CHEMBL1200845 N
Chemical data
Formula C24H32ClFO5
Molecular mass 454.959 g/mol
  • ClCC(=O)[C@]45OC(O[C@@H]5C[C@@H]2[C@@]4(C[C@H](O)[C@]3(F)[C@@]1(/C(=C\C(=O)CC1)CC[C@@H]23)C)C)(C)C
  • InChI=1S/C24H32ClFO5/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,26)17(28)11-22(16,4)24(19,31-20)18(29)12-25/h9,15-17,19,28H,5-8,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1 N
  • Key:MUQNGPZZQDCDFT-JNQJZLCISA-N N
 NYesY (what is this?)  (verify)

Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification.[1] It is used topically (in a 0.05% cream provided as Halog) in the treatment of certain skin conditions.

References

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