Ipidacrine

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File:Ipidacrine.svg
Systematic (IUPAC) name
2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-amine
Clinical data
Trade names Neiromidin
Legal status
  • US: Not FDA approved; unscheduled
Identifiers
ATC code N06DA05 (WHO)
PubChem CID: 604519
ChemSpider 525510
ChEMBL CHEMBL130880
Synonyms Amiridine; NIK-247
Chemical data
Formula C12H16N2
Molecular mass 188.27 g/mol
  • C1CCc2c(c(c3c(n2)CCC3)N)C1
  • InChI=1S/C12H16N2/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12/h1-7H2,(H2,13,14)
  • Key:YLUSMKAJIQOXPV-UHFFFAOYSA-N

Ipidacrine (Neiromidin) is a drug first synthesized by the National Research Center for Biologically Active Compounds in the Russian Federation. This compound is a derivative of 4-aminopyridine and is structurally similar to tacrine.[1]

Ipidacrine is a reversible acetylcholinesterase inhibitor used in memory disorders of different origins.[2][3][4]

Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.[5]

References

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  5. Neiromidin Product Information