JWH-307

JWH-307

Systematic (IUPAC) name
(5-(2-fluorophenyl)-1-pentylpyrrol-3-yl)-naphthalen-1-ylmethanone
Clinical data
Legal status	DE: Anlage II (Prohibited)
Identifiers
CAS Number	914458-26-7 Y
PubChem	CID: 16049783
ChemSpider	13178178
Chemical data
Formula	C26H24FNO
Molecular mass	385.472 g/mol
SMILES CCCCCN1C=C(C=C1C2=CC=CC=C2F)C(=O)C3=CC=CC4=CC=CC=C43
InChI InChI=1S/C26H24FNO/c1-2-3-8-16-28-18-20(17-25(28)23-13-6-7-15-24(23)27)26(29)22-14-9-11-19-10-4-5-12-21(19)22/h4-7,9-15,17-18H,2-3,8,16H2,1H3 Key:WYNZPDDTQGVCLZ-UHFFFAOYSA-N
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JWH-307 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB₁ and CB₂ receptors. It is somewhat selective for the CB₂ subtype, with a Ki of 7.7nM at CB₁ vs 3.3nM at CB₂. It was discovered by, and named after, Dr. John W. Huffman. JWH-307 was detected as an ingredient in synthetic cannabis smoking blends in 2012, initially in Germany.

See also

• JWH-147