Joseph Sambrook
| Joseph Sambrook | |
|---|---|
| Born | 1 March 1939 Liverpool, England |
| Residence | Melbourne, Australia |
| Fields | Molecular biology |
| Institutions | MRC Laboratory of Molecular Biology, Salk Institute for Biological Studies, Cold Spring Harbor Laboratory, University of Texas Southwestern Medical Center, Peter MacCallum Cancer Centre |
| Alma mater | Australian National University |
| Known for | Laboratory manual Molecular Cloning, work on oncoviruses |
| Notable awards | Victorian Government Leadership and Innovation Award, Elected Fellow of the Australian Academy of Sciences and the Royal Society |
Joseph Frank Sambrook (born 1 March 1939 in Liverpool, England) is a British molecular biologist known for his studies of DNA oncoviruses and the molecular biology of normal and cancerous cells. He currently[when?] resides in Melbourne, Australia with his wife and daughter.[citation needed]
Education and early career
Sambrook was educated at the University of Liverpool (BSc (hons) 1962) and obtained his PhD at the Australian National University in 1966. He did postdoctoral research at the MRC Laboratory of Molecular Biology (1966–67) and the Salk Institute for Biological Studies (1967–69). In 1969 he was hired by James D. Watson to work at the Cold Spring Harbor Laboratory in New York. Watson has been reported to say this was the best hiring decision he ever made. Joe was responsible for creating a combative creative environment at CSHL that fomented discovery. Subsequently he worked at the University of Texas Southwestern Medical Center (Dallas).[1]
Achievements
Sambrook is best known for his studies on DNA tumor viruses and the molecular biology of normal and neoplastic cells. His Tumour Virus Group at Cold Spring Harbor identified and mapped all of the major genes of adenoviruses and SV40, determined their transcriptional control in infected and transformed cells, and elucidated the mechanism of integration of these viruses into the genome of the host cell.[citation needed] He has also made important contributions to the understanding of intracellular traffic and protein folding and is an influential leader in the field of the molecular genetics of human cancer.[citation needed]
Sambrook is a former Director of Research at the Peter MacCallum Cancer Centre in Melbourne[2][3] and is an elected Fellow of the Australian Academy of Sciences[4] and the Royal Society.[5] He was the founder and director of the Kathleen Cunningham Consortium for research into familial breast cancer, KConFab, that was established in 1995. [6]
Sambrook has published three editions of the best-selling, highly influential laboratory manual Molecular Cloning.[7] He is also co-editor of Inspiring Science: Jim Watson and the Age of DNA and Life Illuminated: Selected Papers from Cold Spring Harbor Volume 2, 1972–1994. All three books were published by Cold Spring Harbor Laboratory Press.
In 2009 he was awarded the "Victorian Government Leadership and Innovation Award".[1]
References
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- Use British English from February 2013
- Use dmy dates from March 2011
- Vague or ambiguous time from December 2014
- Articles with unsourced statements from April 2010
- Articles with unsourced statements from February 2007
- 1939 births
- People from Liverpool
- Living people
- Virologists
- Fellows of the Royal Society
- Fellows of the Australian Academy of Science
- Scientists from Liverpool
- University of Texas Southwestern Medical Center faculty
