KML-010

KML-010

Systematic (IUPAC) name
8-[4-(4-fluorophenyl)-4-oxobutyl]-1-methyl-1,3,8-triazaspiro[4.5]decan-4-one
Identifiers
PubChem	CID: 10404584
ChemSpider	8580022 Y
Chemical data
Formula	C18H24FN3O2
Molecular mass	333.400 g/mol
SMILES O=C1NCN(C)C1(CC2)CCN2CCCC(=O)c(cc3)ccc3F
InChI InChI=1S/C18H24FN3O2/c1-21-13-20-17(24)18(21)8-11-22(12-9-18)10-2-3-16(23)14-4-6-15(19)7-5-14/h4-7H,2-3,8-13H2,1H3,(H,20,24) Key:GRADLHIYNHRBCW-UHFFFAOYSA-N
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KML-010 is a drug derived from spiperone. It functions as a highly selective 5-HT_2A receptor antagonist, with negligible affinity for the 5-HT_1A or 5-HT_2C receptors, and over 400-fold lower affinity for the D₂ receptor in comparison to spiperone.

See also

• Spiperone