L-745,870

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L-745,870
L-745870 structure.png
Systematic (IUPAC) name
3-([4-(4-chlorophenyl)piperazin-1-yl]methyl)-1H-pyrrolo[2,3-b]pyridine
Identifiers
CAS Number 158985-00-3 YesY
PubChem CID: 5311200
IUPHAR/BPS 3303
ChemSpider 4470720 N
ChEMBL CHEMBL267014 N
Chemical data
Formula C18H19ClN4
Molecular mass 326.822 g/mol
  • c1cc2c(c[nH]c2nc1)CN3CCN(CC3)c4ccc(cc4)Cl
  • InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) N
  • Key:OGJGQVFWEPNYSB-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

L-745,870 is a drug which acts as a dopamine receptor antagonist selective for the D4 subtype, and has antipsychotic effects in animal models, though it was not effective in human trials.[1][2][3]

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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