Levobunolol

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Levobunolol
Levobunolol structural formulae.png
Systematic (IUPAC) name
(S)-5-{[3-(tert-Butylamino)-2-hydroxypropyl]oxy}-3,4-dihydronaphthalen-1(2H)-one
Clinical data
Trade names Betagan
AHFS/Drugs.com monograph
MedlinePlus a686011
Pregnancy
category
  • C
Legal status
Routes of
administration
Topical (eye drops)
Pharmacokinetic data
Biological half-life 20 hours
Identifiers
CAS Number 47141-42-4 YesY
ATC code S01ED03 (WHO)
PubChem CID: 39468
IUPHAR/BPS 570
DrugBank DB01210 YesY
ChemSpider 36089 YesY
UNII G6317AOI7K YesY
KEGG D08115 YesY
ChEBI CHEBI:6438 YesY
ChEMBL CHEMBL1201237 N
Chemical data
Formula C17H25NO3
Molecular mass 291.385 g/mol
  • O=C2c1cccc(OC[C@@H](O)CNC(C)(C)C)c1CCC2
  • InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1 YesY
  • Key:IXHBTMCLRNMKHZ-LBPRGKRZSA-N YesY
 NYesY (what is this?)  (verify)

Levobunolol (AK-Beta, Liquifilm, Betegan) is a non-selective beta blocker. It is used topically to manage glaucoma.

References

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