Linda Hsieh-Wilson
| Linda Carol Hsieh-Wilson | |
|---|---|
| Fields | Chemical neurobiology |
| Institutions | California Institute of Technology |
| Alma mater | University of California, Berkeley |
| Doctoral advisor | Peter G. Schultz |
Linda Carol Hsieh-Wilson is an American chemist. She is known for her work in chemical neurobiology and is currently a professor of chemistry at the California Institute of Technology. She is also a Howard Hughes Medical Institute investigator and an adjunct professor at the Semel Institute for Neuroscience and Human Behavior at the University of California, Los Angeles.
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Biography
Hsieh-Wilson received her Bachelor's degree in chemistry at Yale University. After graduating, she completed her Ph.D. in 1996 at the University of California, Berkeley, where she worked with Peter G. Schultz on antibody-based catalysis.[1] She studied the neuronal targeting protein spinophilin at the Rockefeller University with Nobel Laureate Paul Greengard until 2000.[2] She then obtained an appointment at the Department of Chemistry at the California Institute of Technology in 2000 as an assistant professor and became an associate professor of chemistry and an investigator at the Howard Hughes Medical Institute in 2005.[3][4] She was appointed a full professor of chemistry at the California Institute of Technology in 2010.
Research interests
Hsieh-Wilson's research is at the interface between organic chemistry and neuroscience.[5] She investigates how glycans affect the structure and function of proteins in the nervous system. Her laboratory has developed a chemoenzymatic method to tag proteins that have been appended with a dynamic form of glycosylation called O-GlcNAc.[6] Her work with glycosaminoglycan microarrays has significantly advanced an understanding of specific sulfated glycosaminoglycans in neuronal communication, learning, and memory as well as advanced the field of chemical biology.[7] She has demonstrated how fucosylation can modulate neurite growth and neuronal morphology.[8]
Notable papers
The Web of Science lists 51 publications in peer-reviewed scientific journals that have been cited over 1200 times, leading to an h-index of 21.[9] Her three most cited papers (>90 times) are:[9]
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Awards and honors
- Beckman Young Investigators Award (2000)
- Research Corporation Research Innovation Award (2000)
- Alfred P. Sloan Fellowship (2003)
- Eli Lilly Award in Biological Chemistry (2006)
- Arthur C. Cope Scholar Award (2008)[10]
References
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