Loracarbef
From Infogalactic: the planetary knowledge core
File:Loracarbef.png | |
Systematic (IUPAC) name | |
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(6R,7S)-7-[[(2S)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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Clinical data | |
Trade names | Lorabid |
AHFS/Drugs.com | monograph |
MedlinePlus | a601206 |
Pharmacokinetic data | |
Protein binding | 25% |
Identifiers | |
CAS Number | 76470-66-1 |
ATC code | J01DC08 (WHO) |
PubChem | CID: 5284584 |
DrugBank | DB00447 |
ChemSpider | 4447634 |
UNII | W72I5ZT78Z |
KEGG | D08143 |
ChEMBL | CHEMBL1013 |
Chemical data | |
Formula | C16H16ClN3O4 |
Molecular mass | 349.769 g/mol |
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Loracarbef is an antibiotic.[1] It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. Loracarbef is a synthetic "carba" analog of cefaclor, and is more stable chemically.
History
Loracarbef received FDA approval in 1991 and it was marketed under the trade name Lorabid. Its use was discontinued in 2006.[citation needed]
Side effects
Diarrhea is the most common adverse effect with loracarbef. Side effects are more frequently seen with children under the age of twelve.
References
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External links
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