Lowest-observed-adverse-effect level

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The lowest-observed-adverse-effect level (LOAEL) is the lowest concentration or amount of a substance found by experiment or observation that causes an adverse alteration of morphology, function, capacity, growth, development, or lifespan of a target organism distinguished from normal organisms of the same species under defined conditions of exposure.[1] Federal agencies use set approval standards below this level.

The United States Environmental Protection Agency defines LOAEL as the 'lowest level of a chemical stressor evaluated in a toxicity test that shows harmful effects on a plant or animal. While LOAELs and LOAECs are similar, they are not interchangeable. A LOAEL refers to a dose of chemical that is ingested, while a LOAEC refers to direct exposure to a chemical (e.g., through gills or the skin).'.[2]

See also

References

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  2. http://www.epa.gov/OCEPAterms/lterms.html


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