Lysosomal lipase

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lipase A, lysosomal acid, cholesterol esterase (Wolman disease)
Identifiers
Symbol LIPA
Entrez 3988
HUGO 6617
OMIM 278000
RefSeq NM_000235
UniProt P38571
Other data
EC number 3.1.1.13
Locus Chr. 10 q23.2-23.3

Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.

Clinical significance

A deficiency associated with Lysosomal Acid Lipase Deficiency, Wolman disease, and cholesteryl ester storage disease.

Chlorpromazine is an inhibitor of lysosomal lipase.[1]

A genome wide survey suggests that lysosomal lipase A (located at chromosome 10q23.31) is associated with coronary artery disease in humans.[2]

References

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External links

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