MBX-8025

MBX-8025

Systematic (IUPAC) name
{2-methyl-4-[5-methyl-2-(4-trifluoromethyl-phenyl)-2H-[1,2,3]triazol-4-ylmethylsylfanyl]-phenoxy}-acetic acid
Clinical data
Pregnancy category	N/A
Legal status	Investigational
Identifiers
PubChem	CID: 11539381
ChemSpider	9714160
Chemical data
Formula	C20H18F3N3O3S
Molecular mass	437.435
SMILES FC(F)(F)c1ccc(cc1)n2nc(c(n2)CSc3cc(c(OCC(=O)O)cc3)C)C
InChI InChI=1S/C20H18F3N3O3S/c1-12-9-16(7-8-18(12)29-10-19(27)28)30-11-17-13(2)24-26(25-17)15-5-3-14(4-6-15)20(21,22)23/h3-9H,10-11H2,1-2H3,(H,27,28) Key:XJHXZGHPCAKRFK-UHFFFAOYSA-N

MBX-8025 is a PPARδ receptor agonist that is being investigated for drug use by Metabolex. According to a press release they are examining its potential use for the treatment of dyslipidemia, metabolic syndrome, type 2 diabetes, and non-alcoholic steatohepatitis. The compound, formerly known as RWJ-800025, was licensed from Janssen Pharmaceutica NV.

See also

• GW501516
• GFT505
• Peroxisome proliferator-activated receptor