Masoprocol
From Infogalactic: the planetary knowledge core
File:Masoprocol.svg | |
Systematic (IUPAC) name | |
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4-[(2R,3S)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
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Clinical data | |
Trade names | Actinex |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
Pregnancy category |
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Routes of administration |
Topical |
Pharmacokinetic data | |
Bioavailability | Very low |
Identifiers | |
CAS Number | 500-38-9 |
ATC code | L01XX10 (WHO) |
PubChem | CID: 71398 |
IUPHAR/BPS | 4265 |
DrugBank | DB00179 |
ChemSpider | 64490 |
UNII | 7BO8G1BYQU |
ChEBI | CHEBI:73468 |
ChEMBL | CHEMBL313972 |
Chemical data | |
Formula | C18H22O4 |
Molecular mass | 302.365 g/mol |
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Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.
Also called nordihydroguaiaretic acid, NDGA, and actinex.
Mechanism
Nordihydroguaiaretic acid is an antioxidant, and it may block certain enzymes needed for tumor growth.
It is a lipoxygenase inhibitor.[1]
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
External links
- MedlinePlus Drug Information
- Actinex entry in the public domain NCI Cancer Dictionary
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