Minaprine

Minaprine

Systematic (IUPAC) name
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ (Prescription only)
Routes of administration	Oral
Pharmacokinetic data
Biological half-life	2-2.5 hours
Identifiers
CAS Number	25905-77-5 Y
ATC code	N06AX07 (WHO)
PubChem	CID: 4199
ChemSpider	4054 N
UNII	00U7GX0NLM N
KEGG	D05039 Y
ChEMBL	CHEMBL278819 N
Chemical data
Formula	C17H22N4O
Molecular mass	298.383 g/mol
SMILES CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3
NY (what is this?)  (verify)

Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is an antidepressant that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.

A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.

See also

• Monoamine oxidase inhibitor