Nialamide

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Nialamide
Nialamide.svg
Systematic (IUPAC) name
N-benzyl-3-(N'-(pyridine-4-carbonyl)hydrazino)propanamide
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • AU: S4 (Prescription only)
Routes of
administration
Oral
Identifiers
CAS Number 51-12-7 YesY
ATC code N06AF02 (WHO)
PubChem CID: 4472
DrugBank DB04820 YesY
ChemSpider 4317 YesY
UNII T2Q0RYM725 YesY
KEGG D07337 YesY
Chemical data
Formula C16H18N4O2
Molecular mass 298.34 g/mol
  • O=C(NNCCC(=O)NCc1ccccc1)c2ccncc2
  • InChI=1S/C16H18N4O2/c21-15(18-12-13-4-2-1-3-5-13)8-11-19-20-16(22)14-6-9-17-10-7-14/h1-7,9-10,19H,8,11-12H2,(H,18,21)(H,20,22) YesY
  • Key:NOIIUHRQUVNIDD-UHFFFAOYSA-N YesY
  (verify)

Nialamide (Niamid, Niamide, Nuredal, Surgex) is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant.[1] It was withdrawn by Pfizer several decades ago due to the risk of hepatotoxicity.[2][3]

See also

References

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