Noxiptiline

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Noxiptiline
Skeletal formula of noxiptilin
Space-filling model of the noxiptiline molecule
Systematic (IUPAC) name
10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one O-[2-dimethylamino)ethyl]oxime
Clinical data
Legal status
  • ℞ (Prescription only)
Routes of
administration		 Oral
Identifiers
CAS Number 4985-15-3 YesY
ATC code none
PubChem CID: 21087
ChemSpider 19832 YesY
UNII DF7D3NY7EL YesY
ChEMBL CHEMBL1697689 N
Chemical data
Formula C19H22N2O
Molecular mass 294.39 g/mol
  • O(\N=C2\c1c(cccc1)CCc3c2cccc3)CCN(C)C
  • InChI=1S/C19H22N2O/c1-21(2)13-14-22-20-19-17-9-5-3-7-15(17)11-12-16-8-4-6-10-18(16)19/h3-10H,11-14H2,1-2H3 YesY
  • Key:GPTURHKXTUDRPC-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Noxiptiline (Agedal, Elronon, Nogedal), also known as noxiptyline and dibenzoxine, is a tricyclic antidepressant (TCA) that was introduced in Europe in the 1970s for the treatment of depression.[1][2][3] It has imipramine-like effects,[4] acting as a serotonin and norepinephrine reuptake inhibitor, among other properties.[5][6] Of the TCAs, noxiptiline has been described as one of the most effective, rivaling amitriptyline in clinical efficacy.[7][8]

See also

References

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