Nuciferine
From Infogalactic: the planetary knowledge core
Names | |
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IUPAC name
(6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
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Other names
(R)-1,2-Dimethoxyaporphine
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Identifiers | |
475-83-2 | |
ChEMBL | ChEMBL464529 |
ChemSpider | 9740 |
Jmol 3D model | Interactive image |
PubChem | 3108374 |
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Properties | |
C19H21NO2 | |
Molar mass | 295.376 g/mol |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |
Infobox references | |
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade.[1] It induces sedation, hypothermia, ptosis, and (in higher doses) catalepsy; it inhibits spontaneous motor activity, conditioned avoidance response, amphetamine toxicity and stereotypy. Nuciferine may also potentiate morphine analgesia. The median lethal dose in mice is 289 mg/kg. It is structurally related to apomorphine.[2][3]
See also
References
- ↑ Farrell MS et al (2016): "In Vitro and In Vivo Characterization of the Alkaloid Nuciferine", PLoS One. PMID 26963248
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Spess, David L. Errors in Alkaloids of Nelumbo and Nymphaea species, 2011, academia.edu
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