Osanetant

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Osanetant
Osanetant.png
Systematic (IUPAC) name
N-(1-{3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl]-N-methylacetamide
Identifiers
CAS Number 160492-56-8 YesY
ATC code none
PubChem CID: 219077
IUPHAR/BPS 2110
ChemSpider 189901 N
UNII K7G81N94DT YesY
ChEMBL CHEMBL346178 N
Chemical data
Formula C35H41Cl2N3O2
Molecular mass 606.625 g/mol
  • CC(=O)N(C)C1(CCN(CC1)CCC[C@@]2(CCCN(C2)C(=O)C3=CC=CC=C3)C4=CC(=C(C=C4)Cl)Cl)C5=CC=CC=C5
  • InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1 N
  • Key:DZOJBGLFWINFBF-UMSFTDKQSA-N N
 NYesY (what is this?)  (verify)

Osanetant (SR-142,801) was a neurokinin 3 receptor antagonist developed by Sanofi-Synthélabo, which was being researched for the treatment of schizophrenia, but was discontinued.[1][2] It was the first non-peptide NK3 antagonist developed in the mid-1990s,[3][4] Other potential applications for osanetant is in the treatment of drug addiction, as it has been found to block the effects of cocaine in animal models.[5][6]

References

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  1. REDIRECT Template:Peptide receptor modulators


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