Oxadiazole
From Infogalactic: the planetary knowledge core
Oxadiazole is a heterocyclic aromatic chemical compound with the molecular formula C2H2N2O. There are four isomers of oxadiazole:
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1,2,3-oxadiazole.svg
1,2,3-oxadiazole
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1,2,4-oxadiazole.svg
1,2,4-oxadiazole
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1,2,5-oxadiazole.svg
1,2,5-oxadiazole
(furazan) -
1,3,4-oxadiazole.svg
1,3,4-oxadiazole
1,2,4-Oxadiazole, 1,2,5-oxadiazole, and 1,3,4-oxadiazole are known, but the 1,2,3-isomer is unstable and reverts to the diazoketone tautomer.[1] The stable oxadiazoles appear in a variety of pharmaceutical drugs including raltegravir, butalamine, fasiplon, oxolamine, and pleconaril.
References
- ↑ Heterocyclic Chemistry, 3rd Edition, J. A. Joule, K. Mills, and G.F. Smith, page 452
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