P2RY8

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.[1][2]

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.[2]

Clinical relevance

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.[3]

See also

References

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  2. 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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