PCCG-4

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PCCG-4
PCCG-4 structure.png
Systematic (IUPAC) name
(2S,1'S,2'S,3'R)-2-(2'Carboxy-3'-phenylcyclopropyl)glycine
Identifiers
PubChem CID: 5311344
IUPHAR/BPS 3335
ChemSpider 4470843 YesY
ChEMBL CHEMBL39573 YesY
Chemical data
Formula C12H13NO4
Molecular mass 235.235 g/mol
  (verify)

PCCG-4 is a research drug which acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3), with slight selectivity for mGluR2 although not sufficient to distinguish mGluR2 and mGluR3 responses from each other. It is used in research into the function of the group II metabotropic glutamate receptors.[1][2][3][4][5]

References

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  2. Thomsen C, Bruno V, Nicoletti F, Marinozzi M, Pellicciari R (July 1996). "(2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a potent and selective antagonist of type 2 metabotropic glutamate receptors". Molecular Pharmacology. 50 (1): 6–9. PMID 8700119. <templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
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