PNU-120,596

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PNU-120,596
PNU-120596 structure.png
Systematic (IUPAC) name
1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea
Identifiers
CAS Number 501925-31-1 YesY
PubChem CID: 311434
IUPHAR/BPS 3991
ChemSpider 275409 N
ChEMBL CHEMBL257591 N
Chemical data
Formula C13H14ClN3O4
Molecular mass 311.720
  • COc1cc(OC)c(Cl)cc1NC(=O)Nc2noc(C)c2
  • InChI=1S/C13H14ClN3O4/c1-7-4-12(17-21-7)16-13(18)15-9-5-8(14)10(19-2)6-11(9)20-3/h4-6H,1-3H3,(H2,15,16,17,18) N
  • Key:CEIIEALEIHQDBX-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

PNU-120596 is a drug that acts as a potent and selective positive allosteric modulator for the α7 subtype of neural nicotinic acetylcholine receptors.[1][2] It is used in scientific research into cholinergic regulation of dopamine and glutamate release in the brain.[3][4][5]

References

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