Perflenapent

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Perflenapent
Structural formula of perflenapent
Ball-and-stick model of the perflenapent molecule
Names
IUPAC name
Dodecafluoropentane
Other names
Perfluoropentane
Identifiers
678-26-2
ChemSpider 12154
Jmol 3D model Interactive image
PubChem 12675
  • InChI=1S/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
    Key: NJCBUSHGCBERSK-UHFFFAOYSA-N
  • InChI=1/C5F12/c6-1(7,2(8,9)4(12,13)14)3(10,11)5(15,16)17
    Key: NJCBUSHGCBERSK-UHFFFAOYAH
  • C(C(C(F)(F)F)(F)F)(C(C(F)(F)F)(F)F)(F)F
Properties
C5F12
Molar mass 288.04 g·mol−1
Density 1.63 g/mLl (liquid, 25 °C) [1]
1.59 g/ml (liquid, 35 °C)
Melting point −115 °C (−175 °F; 158 K)
Boiling point 28 °C (82 °F; 301 K)
Vapor pressure 83.99 kPa (25 °C)
Viscosity 0.652 mPa*s (25 °C)
Thermochemistry
0.26 cal/(g • K)
Pharmacology
ATC code V08DA03
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Perflenapent (INN/USAN), or perfluoropentane (PFP), is a fluorocarbon. It has several biomedical applications including: propellant for pressurized metered dose inhalers;[2] gas core in microbubble ultrasound contrast agents;[3] and occlusion therapy via the conversion of nanometer liquid droplets into micrometer sized gas microbubbles (acoustic droplet vaporization).[4]

References

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  2. Rogueda, P. G. A. HPFP, a Model Propellant for pMDIs. Drug Dev. Ind. Phar. 2003, 29, 39
  3. Liu, Y., Miyoshi, H., and Nakamura, M. Encapsulated ultrasound microbubbles: Therapeutic application in drug/gene delivery. J. Controlled Release 2006, 114, 89− 99
  4. D. Bardin, T. D. Martz, P. S. Sheeran, R. Shih, P. A. Dayton, and A. P. Lee, “High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy,” Lab on a Chip, vol. 11, no. 23, p. 3990, 2011.


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