Perkin reaction
From Infogalactic: the planetary knowledge core
| Perkin reaction | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Named after | William Henry Perkin | ||||||||||
| Reaction type | Condensation reaction | ||||||||||
| Reaction | |||||||||||
|
|||||||||||
| Identifiers | |||||||||||
| RSC ontology ID | RXNO:0000003  |
||||||||||
 (what is this?) (verify) |
|||||||||||
The Perkin reaction is an organic reaction developed by William Henry Perkin that is used to make cinnamic acids. It gives an α,β-unsaturated aromatic acid by the aldol condensation of an aromatic aldehyde and an acid anhydride, in the presence of an alkali salt of the acid.[1][2] The alkali salt acts as a base catalyst, and other bases can be used instead.[3]
Several reviews have been written.[4][5][6]
Reaction mechanism
The above mechanism is not universally accepted, as several other versions exist, including decarboxylation without acetic group transfer.[7]
See also
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ House, H. O. (1972) Modern Synthetic Reactions, W. A. Benjamin, Menlo Park, California, 2nd ed, pp. 660–663
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Bansal, Raj K. (1998) Organic Reaction Mechanisms, Tata McGraw Hill, 3rd Edition , pp. 199–201, ISBN 9780470858585 doi:10.1002/0470858583.
