Pharyngeal pouch (embryology)

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Pharyngeal pouch
Kiemenbogen.jpg
Pattern of the branchial arches. I-IV branchial arches, 1-4 pharyngeal pouches (inside) and/or pharyngeal grooves (outside)
a Tuberculum laterale
b Tuberculum impar
c Foramen cecum
d Ductus thyreoglossus
e Sinus cervicalis
Gray979.png
Floor of pharynx of human embryo about twenty-six days old.
Details
Latin sacci pharyngei
Carnegie stage 10
Identifiers
Code TE E5.4.2.0.0.1.1
TA Lua error in Module:Wikidata at line 744: attempt to index field 'wikibase' (a nil value).
TH {{#property:P1694}}
TE {{#property:P1693}}
FMA {{#property:P1402}}
Anatomical terminology
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

In the embryonic development of vertebrates, pharyngeal pouches form on the endodermal side between the pharyngeal arches. The pharyngeal grooves (or clefts) form the lateral ectodermal surface of the neck region to separate the arches.

The pouches line up with the clefts,[1] and these thin segments become gills in fish.

Specific pouches

First pouch

The endoderm lines the future auditory tube (Pharyngotympanic Eustachian tube), middle ear, mastoid antrum, and inner layer of the tympanic membrane. Derivatives of this pouch are supplied by Mandibular nerve.

Second pouch

Third pouch

  • The third pouch possesses Dorsal and Ventral wings. Derivatives of the dorsal wings include the inferior parathyroid glands, while the ventral wings fuse to form the cytoreticular cells of the thymus. The main nerve supply to the derivatives of this pouch is Cranial Nerve IX, glossopharyngeal nerve.

Fourth pouch

Derivatives include:

  • superior parathyroid glands and ultimobranchial body which forms the parafollicular C-Cells of the thyroid gland.
  • Musculature and cartilage of larynx (along with the sixth pharyngeal arch).
  • Nerve supplying these derivatives is Superior laryngeal nerve.

Fifth pouch

  • Rudimentary structure, becomes part of the fourth pouch contributing to thyroid C-cells.[2]

Sixth pouch

  • The sixth pouch does not exist. The fourth and sixth arches contribute to the formation of the musculature and cartilage of the larynx. Nerve supply is by Recurrent laryngeal nerve.

See also

References

External links