Porphobilinogen

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Porphobilinogen
Porphobilinogen.png
Names
IUPAC name
3-[5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
Identifiers
487-90-1 YesY
ChemSpider 995 N
DrugBank DB02272 YesY
EC Number 207-666-3
Jmol 3D model Interactive image
MeSH Porphobilinogen
PubChem 1021
UNII 74KHC72QXK N
  • InChI=1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16) N
    Key: QSHWIQZFGQKFMA-UHFFFAOYSA-N N
  • InChI=1/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16)
    Key: QSHWIQZFGQKFMA-UHFFFAOYAF
  • C1=C(C(=C(N1)CN)CC(=O)O)CCC(=O)O
Properties
C10H14N2O4
Molar mass 226.229
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Porphobilinogen (PBG) is a pyrrole involved in porphyrin metabolism.

It is generated from aminolevulinate (ALA) by the enzyme ALA dehydratase. PBG is then converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase, also known as hydroxymethylbilane synthase.

Acute intermittent porphyria causes an increase in urinary porphobilinogen.[1]

References

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