Portal:Companies

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Laboratories at Icos
Icos Corporation was the largest biotechnology company in the U.S. state of Washington before it was sold to Eli Lilly and Company in 2007.

Co-founded in 1989 by George B. Rathmann, a pioneer in the industry and Chief Executive Officer (CEO) and co-founder of Amgen, Icos focused on the development of drugs to treat inflammatory disorders.

During its 17-year history, the company conducted clinical trials of 12 drugs, three of which reached the last phase of clinical trials. Icos also manufactured antibodies for other biotechnology companies.

Icos is famous for tadalafil (Cialis), a drug used to treat erectile dysfunction.

This drug was discovered by GlaxoSmithKline, developed by Icos, and manufactured and marketed in partnership with Eli Lilly. Boosted by a unique advertising campaign led by the Grey Worldwide Agency, sales from Cialis allowed Icos to become profitable in 2006.

Cialis was the only drug developed by the company to be approved. LeukArrest, a drug to treat shock, and Pafase, developed for sepsis, were both tested in phase III clinical trials, but testing was discontinued after unpromising results during the trials. Eli Lilly acquired Icos in January 2007, and most of Icos's workers were laid off soon after.

CMC Biopharmaceuticals, a Danish contract manufacturer, bought the remnants of Icos and retained the remaining employees.

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Peugeot 206 WRC.jpg
Credit: Christopher Batt
Juuso Pykälistö in his Peugeot 206 WRC during the 2003 Swedish Rally. Peugeot is a major French car brand, part of the PSA Peugeot Citroën group. It is the second largest automaker in Europe behind Volkswagen. Peugeot's world headquarters are in Avenue de la Grande Armée, Paris, close to Porte Maillot, but the Peugeot company and family is originally from Sochaux. Peugeot retains a large manufacturing plant in Sochaux which is also home to the Peugeot Museum.

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Largest market capitalization in Q2 2015
1 United States  Apple Inc.
2 United States  Microsoft
3 United States  Exxon Mobil
4 United States  Berkshire Hathaway
5 United States  Google
6 China  PetroChina
7 China  ICBC
8 United States  Wells Fargo
9 United States  Johnson & Johnson
10 United States  General Electric
More lists and rankings...

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