Profenamine

Profenamine

Systematic (IUPAC) name
N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
Clinical data
AHFS/Drugs.com	International Drug Names
Pharmacokinetic data
Protein binding	93%
Biological half-life	1 to 2 hours
Identifiers
CAS Number	1094-08-2 Y
ATC code	N04AA05 (WHO)
PubChem	CID: 3290
IUPHAR/BPS	7181
DrugBank	DB00392 Y
ChemSpider	3174 Y
UNII	O00T1I1VRN Y
ChEBI	CHEBI:313639 Y
ChEMBL	CHEMBL1206 Y
Chemical data
Formula	C19H24N2S
Molecular mass	312.473 g/mol
SMILES S2c1ccccc1N(c3c2cccc3)CC(N(CC)CC)C
InChI InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 Y Key:CDOZDBSBBXSXLB-UHFFFAOYSA-N Y
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Profenamine (INN, trade names Parsidol, Parsidan, Parkin), also known as ethopropazine (BAN), is a phenothiazine derivative used as an antiparkinsonian agent that has anticholinergic, antihistamine, and antiadrenergic actions. It is also used in the alleviation of the extrapyramidal syndrome induced by drugs such as other phenothiazine compounds, but, like other compounds with antimuscarinic properties, is of no value against tardive dyskinesia.