RBBP8
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene.[1][2][3]
Function
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.[3]
Interactions
RBBP8 has been shown to interact with:
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References
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Further reading
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