RU-58642

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RU-58642
RU58642.svg
Systematic (IUPAC) name
4-[3-(cyanomethyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Identifiers
CAS Number 143782-63-2
PubChem CID: 9840708
ChemSpider 8016425
Chemical data
Formula C15H11F3N4O2
Molecular mass 336.268 g/mol
  • O=C1N(CC#N)C(C)(C)C(=O)N1c(cc2C(F)(F)F)ccc2C#N
  • InChI=1S/C15H11F3N4O2/c1-14(2)12(23)22(13(24)21(14)6-5-19)10-4-3-9(8-20)11(7-10)15(16,17)18/h3-4,7H,6H2,1-2H3
  • Key:ZVWXHSNUBLIKJH-UHFFFAOYSA-N

RU-58642 is a non-steroidal anti-androgen drug with very high affinity and selectivity, which made it among the most potent and effective antiandrogen drugs known at the time of its discovery.[1] It was investigated for topical application for the treatment of baldness, but development did not proceed past initial trial stages, and it is now only used for scientific research into the androgen receptor.[2][3]

References

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  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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