Reticulocytopenia

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Reticulocytopenia
Classification and external resources
Specialty Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value).
ICD-9-CM 282.62
DiseasesDB 10703
Patient UK Reticulocytopenia
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

Reticulocytopenia, also known as an "aplastic crisis" or "marrow failure", is the medical term for an abnormal decrease of reticulocytes in the body. Reticulocytes are immature red blood cells. Reticulocytopenia may be a result of viral parvovirus B19 infection, which invades and destroys red blood cell precursors and halts the red cell production. If infection occurs in individuals with sickle cell anemia[1] or spherocytosis, that will lead to incorporation of two anemia-induced mechanisms: decreased red cell production and hemolysis. The result is a severe anemia (aplastic crisis) which may require blood transfusion.

References

  1. "Sickle Cell Disease - Basic Principles and Clinical Practice" Edited by Stephen H. Embury, Robert P. Hebbel, Narla Mohandas and Martin Steinberg. Copyright 1996 by Lippincott-Raven. Section IV p352.



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