Rodney Robert Porter

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Rodney Porter
Rodney Robert Porter.jpg
Born Rodney Robert Porter
(1917-10-08)8 October 1917
Newton-le-Willows, Lancashire
Died 6 September 1985(1985-09-06) (aged 67)
Nationality English
Fields biochemistry
Institutions
Alma mater
Thesis The free amino groups of proteins (1948)
Doctoral advisor Frederick Sanger[1]
Known for Chemical structure of antibodies
Notable awards

Rodney Robert Porter, CH, FRS[2] (8 October 1917 – 6 September 1985) was an English biochemist[3][4] and Nobel laureate.[5][6][7][8][9][10][11][12]

Education and early life

Born in Newton-le-Willows, St Helens, Lancashire, England, Rodney Robert Porter received his Bachelor of Science degree from the University of Liverpool in 1939 for Biochemistry. He moved to the University of Cambridge where he became Fred Sanger's first PhD student.[1] He was awarded his doctorate in 1948.[13][14]

Career and research

Porter worked for the National Institute for Medical Research for eleven years (1949–1960) before joining St. Mary's Hospital Medical School, Imperial College London and becoming the Pfizer Professor of Immunology. In 1967 he was appointed Whitley Professor of Biochemistry at the University of Oxford, and Fellow of Trinity College, Oxford. His colleague Elizabeth Press (Betty Press) worked with him at NIMR, St Mary's and at Oxford contributing extensively to the work which led to the Nobel Prize.

Awards and honours

Porter was elected a Fellow of the Royal Society (FRS) in 1964.[2] He won the Gairdner Foundation International Award in 1966.[citation needed] In 1972, Porter shared the Nobel Prize for Medicine or Physiology with Gerald M. Edelman for determining the chemical structure of an antibody.[15][16][17][18][19] Using the enzyme papain, he broke the blood's immunoglobin into fragments, making them easier to study. He also looked into how the blood's immunoglobins react with cellular surfaces. He subsequently worked with colleagues Kenneth BM Reid, Robert Sim and Duncan Campbell on developing understanding of the Complement Proteins associated with defence against infection.

In 1991, Raymond Dwek founded the Oxford Glycobiology Institute at the Department of Biochemistry, University of Oxford and this building was named after Porter as the Rodney Porter building.

Death

Porter died in a road accident near Winchester, Hampshire and is survived by his wife and five children.

References

  1. 1.0 1.1 "Rodney Porter Memorial Lectures". Oxford: University of Oxford. Archived from the original on 2015-01-04.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
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  6. Porter, R. R. (1991). "Lecture for the Nobel Prize for physiology or medicine 1972: Structural studies of immunoglobulins. 1972". Scandinavian journal of immunology. 34 (4): 381–389. PMID 1925407.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  7. Hein, H. (1973). "Nobel price for medicine 1972". Fortschritte der Medizin. 91 (4): 167. PMID 4573771.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  8. Datta, R. K.; Datta, B. (1973). "Nobel Prize winners in Medicine (1972)". Journal of the Indian Medical Association. 60 (1): 17–18. PMID 4577220.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  9. Schlesinger, M. (1973). "The 1972 Nobel prize for medicine, G.M. Adelman and R.R. Porter". Harefuah. 84 (1): 41. PMID 4571222.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  10. Harboe, M. (1972). "Nobel prize for immunoglobulin research". Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. 92 (34): 2363–2365. PMID 4568120.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  11. Peterson, P. A. (1972). "1972 Nobel prize in physiology or medicine. The chemical structure of antibodies". Lakartidningen. 69 (44): 5069–5073. PMID 4561953.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  12. Chedd, G. (1973). "Nobel prize for medicine in 1972". Orvosi hetilap. 114 (8): 451–452. PMID 4568717.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
  13. Britannica Information on Rodney Porter
  14. Nobel Prize Biography of Rodney Porter
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  16. "Proceedings of the International Symposium on "The role and significance of international cooperation in the biomedical sciences." Dedicated to the memory of Dr. Rodney R. Porter. Washington, D.C., September 21–23, 1983". Perspect. Biol. Med. 29 (3 Pt 2): S1–229. 1986. PMID 3523420.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>
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  19. Pasternak, Charles A. (1985). "Special issue in memory of Rodney Porter". Biosci. Rep. 5 (10–11): 809–1014. PMID 3913469.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>