Rogletimide

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Rogletimide
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Systematic (IUPAC) name
3-ethyl-3-(pyridin-4-yl)piperidine-2,6-dione
Identifiers
CAS Number 121840-95-7
PubChem CID: 56487
ChemSpider 50963
UNII 14P4QR28QF YesY
Chemical data
Formula C12H14N2O2
Molecular mass 218.25 g/mol
  • O=C1NC(=O)CCC1(c2ccncc2)CC

Rogletimide is a drug related in chemical structure to the sedative glutethimide, but instead having pharmacological activity as a selective aromatase inhibitor similar to the related drug aminoglutethimide, but with no significant sedative effect.[1] This makes it potentially useful in the treatment of some forms of cancer, and with less side effects than aminoglutethimide, but its lower potency caused it to be unsuccessful in clinical trials.[2]

See also

References

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