SIB-1757

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SIB-1757
SIB-1757 structure.png
Systematic (IUPAC) name
6-methyl-2-(phenylazo)-3-pyridinol
Identifiers
CAS Number 31993-01-8 YesY
PubChem CID: 6849066
Chemical data
Formula C12H11N3O
Molecular mass 213.235 g/mol
  • Oc1ccc(C)nc1\N=N\c2ccccc2
  (verify)

SIB-1757 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5.[1] It has anti-hyperalgesia effects in animals.[2] SIB-1757 along with other mGluR5 antagonists has been shown to have neuroprotective and hepatoprotective effects,[3][4] and it is also used to study the role of the mGluR5 receptor in brain development.[5]

References

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