SOX11
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene.[1][2][3]
Function
This intronless gene encodes a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis and adult neurogenesis.[3][4] Tuj1 and Tead2 are suggested as direct target of Sox11.[5][6][7]
Clinical aspect
Mutations in SOX11 are associated to Coffin-Siris syndrome .[8]
See also
References
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Further reading
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