ST-1936

ST-1936

Systematic (IUPAC) name
2-(2-methyl-5-chloro-1H-indol-3-yl)-N,N-dimethylethanamine
Identifiers
CAS Number	1210-81-7 Y
ATC code	none
PubChem	CID: 9921064
Chemical data
Formula	C13H17ClN2
Molecular mass	236.74 g/mol
SMILES CC1=C(CCN(C)C)C2=CC(Cl)=CC=C2N1

ST-1936 (2-methyl-5-chloro-N,N-dimethyltryptamine) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT₆ receptor agonist, with a K_i of 13 nM, and much weaker action at 5-HT_2B and 5-HT₇ subtypes. In animal studies it has been found to increase dopamine and noradrenaline mediated signalling but decreases glutamatergic transmission, and has antidepressant effects.

See also

• EMD-386,088
• EMDT
• 5-Bromo-DMT
• 5-Chloro-AMT