Sphincter of Oddi

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sphincter of Oddi
Gray1057.png
Interior of the descending portion of the duodenum, showing bile papilla.
Details
Latin m. sphincter ampullae
Identifiers
MeSH A03.159.183.079.300.900.600
Dorlands
/Elsevier
s_18/12748595
TA Lua error in Module:Wikidata at line 744: attempt to index field 'wikibase' (a nil value).
TH {{#property:P1694}}
TE {{#property:P1693}}
FMA {{#property:P1402}}
Anatomical terminology
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The sphincter of Oddi (or hepatopancreatic sphincter) is a muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi.[1] The sphincter of Oddi is relaxed by the hormone cholecystokinin (CCK)[2] via vasoactive intestinal peptide (VIP).[3]

Clinical significance

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Opiates can cause spasms of the sphincter of Oddi, leading to increased serum amylase levels.

Other animals

In many mammals (including mice, guinea pigs, dogs and opossums), the smooth muscle around the ampulla of Vater does not form a sphincter.[4]

References

  1. synd/2709 at Who Named It?
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  4. Higashiyama H, Sumitomo H, Ozawa A, Igarashi H, Tsunekawa N, Kurohmaru M, Kanai Y. (2016). Anatomy of the Murine Hepatobiliary System: A Whole-Organ-Level Analysis Using a Transparency Method. The Anatomical Record. 299(2):161-172. doi:10.1002/ar.23287 PMID 26559382
  • Gray's Anatomy, 39th ed. p. 1228.

Further reading

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