Spiramide

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Spiramide
AMI-193 structure.png
Systematic (IUPAC) name
8-[3-(4-Fluorophenoxy)propyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one
Identifiers
CAS Number 510-74-7
ATC code none
PubChem CID: 68186
IUPHAR/BPS 175
ChemSpider 61493
UNII 471LF4O004 YesY
ChEBI CHEBI:64207 YesY
Chemical data
Formula C22H27FN3O2
Molecular mass 384.466 g/mol
  • c2cc(F)ccc2OCCCN3CCC1(CC3)N(CNC1=O)c4ccccc4
  • InChI=1S/C22H26FN3O2/c23-18-7-9-20(10-8-18)28-16-4-13-25-14-11-22(12-15-25)21(27)24-17-26(22)19-5-2-1-3-6-19/h1-3,5-10H,4,11-17H2,(H,24,27)
  • Key:FJUKDAZEABGEIH-UHFFFAOYSA-N
  (verify)

Spiramide (AMI-193) is a selective 5-HT2A, 5-HT1A, and D2 receptor antagonist. It has negligible affinity for the 5-HT2C receptor.[1][2][3]

References

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