Stone of madness

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The stone of folly or the stone of madness refers to a hypothetical procedure in the 15th century involving trepanation and extraction of a stone, thought to be the cause of the patient's madness.[1][2] This procedure is demonstrated in the painting The Extraction of the Stone of Madness by Hieronymus Bosch.[3] The procedure and the painting depicting it inspired the 2002 short film of the same name.[4]

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