Sulfadimethoxine

Sulfadimethoxine

File:Sulfadimethoxine.svg
File:Sulfadimethoxine ball-and-stick model.png
Systematic (IUPAC) name
4-Amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
Clinical data
AHFS/Drugs.com	FDA Professional Drug Information
Identifiers
CAS Number	122-11-2 Y
ATC code	J01ED02 (WHO) QJ01EQ09 (WHO) QP51AG02 (WHO)
PubChem	CID: 5323
DrugBank	DB06150 Y
ChemSpider	5132 Y
UNII	30CPC5LDEX Y
KEGG	D01142 Y
ChEBI	CHEBI:32161 Y
ChEMBL	CHEMBL62193 Y
Chemical data
Formula	C12H14N4O4S
Molecular mass	310.33 g/mol
SMILES COc1cc(nc(n1)OC)NS(=O)(=O)c2ccc(cc2)N
InChI InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) Y Key:ZZORFUFYDOWNEF-UHFFFAOYSA-N Y
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Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antibiotic. Albon is produced by Pfizer Animal Health and is available as an oral suspension, tablet or bolus. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[5] It is most frequently used in veterinary medicine. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.

Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years. It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.

Side Effects

Some side effects include:

• Redness of the eye
• Discharge from the eye
• Other symptoms related to the eye
• Bleeding
• Vomiting and diarrhea
• Increased thirst is common
• Incessant itch

Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[6]

Uses

It can be used for:

• metritis
• tonsillitis
• pharyngitis
• pneumonia
• pyometra
• anal gland infections
• dermatitis
• wounds and abscesses
• enteritis
• salmonellosis
• enteritis associated with coccidiosis in dogs

Actions

It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

External links

• Albon Oral Suspension product overview
• Albon Tablets product overview
• Albon Bolus product overview
• Coccidia Treatment
• Sulfadimethoxine