Suritozole

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Suritozole
Suritozole.svg
Systematic (IUPAC) name
5-(3-fluorophenyl)-2,4-dimethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
Identifiers
CAS Number 110623-33-1 YesY
ATC code none
PubChem CID: 25431
ChemSpider 23743 N
UNII 3H7H68317X YesY
KEGG D05980 YesY
Chemical data
Formula C10H10FN3S
Molecular mass 223.269 g/mol
  • Cn1c(=S)n(C)nc1-c2cccc(F)c2
  • InChI=1S/C10H10FN3S/c1-13-9(12-14(2)10(13)15)7-4-3-5-8(11)6-7/h3-6H,1-2H3 N
  • Key:IWDUZEHNLHFBRZ-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Suritozole (MDL 26,479) is an investigational cognition enhancer. It acts as a partial inverse agonist at the benzodiazepine receptor site on the GABAA ion channel complex, but does not have either anxiogenic or convulsant effects, unlike other BZD inverse agonists such as DMCM.[1] It was investigated for the treatment of depression and Alzheimer's disease,[2] but clinical development seems to have been discontinued.

References

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