TC-1827
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Names | |
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IUPAC name
(S)-N-Methyl-5-(5-pyrimidinyl)-4-penten-2-amine
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Identifiers | |
547741-76-4 Y | |
Jmol 3D model | Interactive image |
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Properties | |
C10H15N3 | |
Molar mass | 177.25 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
TC-1827 is an orally active, selective agonist of the α4β2 nicotinic receptors. Administration of TC-1827 improved memory and learning in a variety in rodents, and increased long-term potentiation in hippocampal slices. In addition, the compound was without significant cardiovascular side effects, except for a small, transient rise in arterial blood pressure. The pro-cognitive effects of TC-1827 last much longer than the short half life (0.2 - 1.0 hours) would suggest.[1]
References
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