Tabernanthine

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Tabernanthine
Tabernanthine.svg
Systematic (IUPAC) name
13-methoxyibogamine
Identifiers
CAS Number 83-94-3
ATC code none
PubChem CID: 442136
ChemSpider 390656
Chemical data
Formula C20H26N2O
Molecular mass 310.43 g/mol

Tabernanthine is an alkaloid found in Tabernanthe iboga.[1]

It has been used in laboratory experiments to study how addiction affects the brain.[2]

Tabernanthine persistently reduced the self-administration of cocaine and morphine in rats.[3]

See also

References

  1. "The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine - Journal of the American Chemical Society (ACS Publications)". 
  2. Levi MS, Borne RF (October 2002). "A review of chemical agents in the pharmacotherapy of addiction". Curr. Med. Chem. 9 (20): 1807–18. PMID 12369879. doi:10.2174/0929867023368980. 
  3. Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW Jr, Carlson JN (September 1994). "Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum.". Brain Res. 657 (1-2): 14–22. PMID 7820611. doi:10.1016/0006-8993(94)90948-2.